Multivitamin Benefits, Side Effects, Sources and Facts

What is multivitamin?

Multivitamins are a combination of many different vitamins that are normally found in foods and other natural sources. Such preparations are often found in the form of tablets, capsules, pastilles, powders, liquids, and injectable formulations. Multivitamin and mineral supplements help ensure one is getting sufficient vitamins and minerals required for the body to function properly.


"When we compare recommendations for vitamin and mineral intakes to actual consumption, many Americans do not even come close to getting what they need for several nutrients," says Meir Stampfer, MD, DrPH, professor of medicine at Harvard Medical School.


For a vitamin formula to be considered complete, it must contain certain key vitamins. These key vitamins are basic to most multivitamin formulas. You must check the label on your multivitamin to make sure it contains the basic twelve.


What is multivitamin used for?

Multivitamins are used to provide vitamins that are not taken in through the diet. Multivitamins are also used to treat vitamin deficiencies (lack of vitamins) caused by illness, pregnancy, poor nutrition, digestive disorders, and many other conditions.


According to the Dietary Guidelines for Americans 2005, adults are often deficient in:



"Certain groups run even higher risks for vitamin and mineral deficits," says Jeffrey Blumberg, PhD, director of the Antioxidants Research Laboratory, and professor of nutrition at Tufts University.


By supplementing the diet with vitamins and minerals, multivitamins can be a valuable tool for those with dietary imbalances or different nutritional needs. People with dietary imbalances may include those on restrictive diets and those who cannot or will not eat a nutritious diet. Pregnant women and elderly adults have different nutritional needs than other adults, and a multivitamin may be indicated by a physician.


Vitamin shortfall: who's at risk?

Over time, small discrepancies in nutrient intakes can prove problematic for a person, particularly for women in their childbearing years, strict vegetarians, and the elderly.


For instance, shortfalls of iron in the childbearing years may lead to anemia. Too little folic acid very early in pregnancy increases the risk of neural tube defects in developing babies. And vitamin B12 deficits, responsible for irreversible nerve damage and faulty cognition, are more likely in people who avoid animal foods, and in people over age 50, whose bodies are often less efficient at absorbing vitamin B12.


Stampfer and Blumberg advocate multivitamins as a way to shore up diets low in nutrients. But, they warn that multivitamins are dietary supplements, not substitutes for healthy eating.


That's because multivitamins lack a number of beneficial compounds for wellness, including phytonutrients, and fiber, found in plant foods. Multivitamins also typically fall short of the recommend daily amount of calcium and other important vitamins and minerals.


"Think of multivitamins as an insurance policy, but don't fool yourself into thinking dietary supplements measure up to the benefits of maintaining a healthy body weight, eating right, and getting regular physical activity," Blumberg says.


"Overall, multivitamins are a minor component of good health, but worthy ones," Stampfer says.


What are the health benefits of multivitamin?

The health benefits of vitamins and minerals in multivitamins include their ability to prevent and treat various diseases including heart problems, high cholesterol levels, eye disorders, and skin disorders. Most of the vitamins also facilitate the body mechanism and perform functions which are not performed by any other nutrient. Multivitamins are beneficial for the following:



The main advantage of taking daily multivitamin supplements is that they are able to make up for anything that is lacking in a person's diet. Those most likely to benefit from taking such a supplement include dieters, allergy sufferers, vegans, fast-food junkies and pregnant women.


Can multivitamins curb chronic disease?

Don't bet on multivitamins to keep you free of heart disease, cancer, and other chronic illness. That's the recommendation of a 2006 State-of-the-Science Conference on Multivitamin/Mineral Supplements and Chronic Disease Prevention from the National Institutes of Health.


In the report, the 13-member panel concluded that more research is needed before suggesting multivitamin use to head off disease in healthy, non-pregnant people.


However, the NIH opinion contradicts earlier findings, including a 2002 study from the Harvard School of Medicine published in the Journal of the American Medical Association. The authors reviewed 35 years worth of research on vitamins and chronic disease, concluding that every adult should take a multivitamin daily as a safe and inexpensive way to optimize health.


Other studies highlight the connection between multivitamin use and well-being, too.


In a group of more than 88,000 women, those who took multivitamins for 15 years or more significantly reduced the risk of colon cancer as compared to those who took multivitamins for less time. The women were part of the Nurses' Health Study at the Harvard School of Public Health. The research was published in the Annals of Internal Medicine.


Another study found that taking a multivitamin reduced the risk of first-time heart attack in a group of Swedish men and women aged 45 to 70.


In bridging nutrient gaps, it is perfectly plausible to think that multivitamins help head off chronic conditions, including osteoporosis and heart disease," Blumberg says.


So why the difference of opinion?


Stampfer, who was a presenter at the NIH conference, says the panel excluded smaller trials and observational studies done with multivitamins, looking only at the results of large randomized trials, considered the gold standard of clinical studies.


However, randomized trials tend to be shorter than other types of studies, which leaves less time to see results.


What multivitamins should I use?

There may be disagreement about multivitamins' capacity to curb chronic conditions. But on balance, the evidence for the benefits of multivitamins far outweigh the potential for harm -- considered extremely low for most healthy people -- even if the effects on health are small, says Stampfer.


If you're convinced you need a multivitamin, how do you decide which one is best for you?


Eating a balanced diet rich in whole grains, fruits, vegetables, legumes (beans), and lean protein sources most of the time means you'd do fine with a multivitamin with 100% or less of the daily value (DV) for a wide array of nutrients. Daily values, listed on food and supplement labels, help you determine how a serving of food or supplement fits into the nutrient needs of a 2,000-calorie eating plan.


When picking a multivitamin, pay particular attention to the following to maximize benefit and minimize risk.


Key vitamins; the basic twelve must be part of your multivitamin



Minerals


No multivitamin formula could ever be considered complete without certain essential minerals.



There are multivitamins for different needs


When selecting a multivitamin one must also consider the different stages in one's life as well as the different nutritional needs of each gender.



When choosing a multivitamin, one may want to consider whole food based vitamins, made from whole food concentrates. The premise is that when taking a whole food multivitamin, you are acquiring your vitamins from a nutrient dense food based source. The body tends to absorb these more easily than traditional multivitamins.


Many people will tell you that you should be able to get all of your nutritional needs met through the food you eat. Unfortunately, due to soil depletion and toxins that erode our bodies' nutritional reserves, we need a little extra help. Therefore, it is wise to choose a good multivitamin to ensure a stronger body and to live more disease free.


What happens if I overdose on multivitamin?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of vitamins A, D, E, or K can cause serious or life-threatening side effects. Certain minerals contained in a multivitamin may also cause serious overdose symptoms if you take too much.


Overdose symptoms may include stomach pain, vomiting, diarrhea, constipation, loss of appetite, hair loss, peeling skin, tingly feeling in or around your mouth, changes in menstrual periods, weight loss, severe headache, muscle or joint pain, severe back pain, blood in your urine, pale skin, and easy bruising or bleeding.


What are the side effects of multivitamins?

Multivitamin and Mineral Supplements - RDA and Side Effects

It is important to be aware of certain side-effects which can result from taking too high a dosage of different vitamins and minerals. In order to ensure one is sticking to a safe amount of key vitamins and minerals, check labels for the RDA, or "recommended daily amount." The RDA provides guidelines as to typical daily requirements of essential vitamins and minerals, although athletes may need more than the average person.


Many multivitamin products contain minerals such as calcium, iron, magnesium, potassium, and zinc. Minerals (especially taken in large doses) can cause side effects such as tooth staining, increased urination, stomach bleeding, uneven heart rate, confusion, and muscle weakness or limp feeling. Read the label of any multivitamin product you take to make sure you are aware of what it contains.


Other side effects associated with taking too high an amount of vitamins and mineral supplements include:



Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.


When taken as directed, multivitamins are not expected to cause serious side effects. Less serious side effects may include:



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.